⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21533953 | 0.79 | — | — | |
| SCHEMBL21690604 | 0.77 | — | — | |
| SCHEMBL24335867 | 0.74 | PKM (0.30) | — | |
| SCHEMBL12528611 | 0.69 | PIK3CD (0.33) | — | |
| SCHEMBL21324893 | 0.67 | — | — | |
| SCHEMBL21325293 | 0.66 | — | — | |
| SCHEMBL18643112 | 0.64 | PIK3CD (0.30) | — | |
| SCHEMBL611663 | 0.62 | POLB (0.35) | — | |
| SCHEMBL19443027 | 0.60 | PER2 (0.36) | — | |
| SCHEMBL25666129 | 0.59 | HRH3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858344-B2 | Hydantoin containing deoxyuridine triphosphatase inhibitors | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-12-08 | — | — | US | disclosed |