Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2276061 | 0.84 | HTR6 (0.63) | HTR6POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL2270572 | 0.83 | HTR6 (0.71) | HTR6POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL426117 | 0.81 | HTR6 (0.68) | HTR6POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL1972911 | 0.81 | HTR6 (0.50) | HTR6POLBL3MBTL1HDAC3HDAC1 | |
| SCHEMBL2268963 | 0.81 | HTR6 (0.54) | HTR6HDAC3HDAC1HDAC2HDAC10 | |
| Hydrochloric Acid SCHEMBL2269614 | 0.80 | HTR6 (0.53) | HTR6HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL2348423 | 0.79 | HTR6 (0.51) | HTR6 | |
| SCHEMBL2348660 | 0.78 | HTR6 (0.50) | HTR6PPARGEPHX2 | |
| SCHEMBL2364813 | 0.76 | HTR6 (0.48) | HTR6HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3226178 | 0.76 | HTR6 (0.56) | HTR6POLBL3MBTL1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998981-B2 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-08-16 | — | — | US | disclosed |
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES, LTD. (IN) | 2010-07-01 | — | — | US | disclosed |
| EP-1919896-B1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LTD (IN) | 2009-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | HTR6, HTR5A, HTR3B | HTR6 1/4885POLB 4745/4885L3MBTL1 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.