SCHEMBL22754245

SCHEMBL22754245

C=C(C)CCCCCN(C)C(=C)/C=C\C=O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35
EPHX2 P34913 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20750966 0.85
SCHEMBL22883643 0.83 TRPA1 (0.42) TRPA1EPHX2
SCHEMBL25148544 0.72 PAOX (0.44) TRPA1EPHX2
SCHEMBL20088725 0.72 EPHX2 (0.33) TRPA1EPHX2
SCHEMBL22743713 0.70 ALDH1A1 (0.31)
SCHEMBL18830537 0.69 EPHX2 (0.48) TRPA1EPHX2
SCHEMBL22297115 0.68 ALDH1A1 (0.55)
SCHEMBL20750766 0.68 ALDH1A1 (0.55)
SCHEMBL10158622 0.68 ALDH1A1 (0.55)
SCHEMBL18807826 0.68 ALDH1A1 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3099681-B1 CYTOTOXIC TUBULYSIN COMPOUNDS AND CONJUGATES THEREOF TUBE PHARMACEUTICALS GMBH (AT) 2020-12-09 EP disclosed