SCHEMBL22754335

SCHEMBL22754335

Cc1cc2c(cc1F)NNN2C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18912143 0.92 DAO (0.31) DAO
SCHEMBL18911865 0.73
SCHEMBL21936692 0.72
SCHEMBL7921005 0.68 ACHE (0.33)
SCHEMBL18912031 0.65
SCHEMBL25043307 0.65
SCHEMBL18911792 0.63 DAO (0.32) DAO
SCHEMBL20707039 0.63 DAO (0.31) DAO
SCHEMBL261036 0.62 ACHE (0.42) DAO
SCHEMBL12483400 0.61 BRPF1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2831073-B1 NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN KINASES RHIZEN PHARMACEUTICALS S A (CH) 2020-12-09 EP disclosed