Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754637 | 0.93 | HDAC8 (0.57) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL12541741 | 0.91 | ALOX5 (0.56) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL12541737 | 0.91 | ALOX5 (0.56) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL12542012 | 0.84 | HDAC8 (0.58) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL12542009 | 0.84 | HDAC8 (0.58) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL7100642 | 0.84 | APP (0.59) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL12695586 | 0.83 | HDAC8 (0.48) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL12695565 | 0.83 | CHRNA7 (0.50) | APPHDAC8PTPN1ALOX5MAPT | |
| SCHEMBL7751094 | 0.83 | HDAC8 (0.62) | APPHDAC8PTPN1MAPTMEN1 | |
| SCHEMBL7751091 | 0.83 | HDAC8 (0.62) | APPHDAC8PTPN1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688860-B1 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES | UNIGEN INC (US) | 2020-12-09 | — | — | EP | disclosed |