Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.40 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755241 | 0.89 | AVPR1A (0.51) | SPRTSHRHTTALDH1A1HPGD | |
| SCHEMBL22754968 | 0.83 | BTK (0.47) | SPRSCD5SCD | |
| SCHEMBL22755149 | 0.83 | TSHR (0.38) | TSHRHTTALDH1A1HPGDNPSR1 | |
| SCHEMBL22755315 | 0.81 | BTK (0.45) | SPRTSHRHTTALDH1A1HPGD | |
| SCHEMBL22755307 | 0.81 | FASN (0.48) | AVPR1AMGLLNPC1TP53MAPT | |
| SCHEMBL22755022 | 0.78 | LIPG (0.40) | NPC1RAB9A | |
| SCHEMBL22755134 | 0.78 | AVPR1A (0.49) | AVPR1ATPSAB1MGLL | |
| SCHEMBL22755324 | 0.77 | TSHR (0.41) | TSHRHTTALDH1A1HPGDNPSR1 | |
| SCHEMBL22755346 | 0.76 | CNR2 (0.39) | TSHRHTTALDH1A1HPGDNPSR1 | |
| SCHEMBL22754916 | 0.76 | HPGD (0.58) | SPRHTTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |