Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755324 | 0.83 | TSHR (0.41) | CNR2HPGDALDH1A1TSHRHTT | |
| SCHEMBL22755149 | 0.82 | TSHR (0.38) | CNR2HPGDALDH1A1TSHRHTT | |
| SCHEMBL22755307 | 0.80 | FASN (0.48) | SMN1; SMN2TP53 | |
| SCHEMBL22754863 | 0.80 | CYP2C9 (0.54) | ALDH1A1HTTL3MBTL1 | |
| SCHEMBL22755241 | 0.79 | AVPR1A (0.51) | HPGDALDH1A1TSHRHTTNPSR1 | |
| SCHEMBL22755075 | 0.78 | ALDH1A1 (0.37) | CNR2HPGDALDH1A1TSHRHTT | |
| SCHEMBL22755336 | 0.78 | TSHR (0.36) | CNR2HPGDALDH1A1TSHRHTT | |
| SCHEMBL22755134 | 0.78 | AVPR1A (0.49) | — | |
| SCHEMBL22755137 | 0.77 | HRH1 (0.45) | HPGDALDH1A1TSHRHTTNPSR1 | |
| SCHEMBL22754859 | 0.76 | SPR (0.45) | HPGDALDH1A1TSHRHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |