Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754962 | 0.88 | MAPT (0.46) | PDE10AMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL22729597 | 0.81 | PDE10A (0.49) | PDE10AMAPTALDH1A1LIPGLMNA | |
| SCHEMBL22754953 | 0.79 | UGCG (0.51) | PDE10AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22754907 | 0.76 | MAPT (0.43) | MAPTALDH1A1LMNAPDE7AMAPK1 | |
| SCHEMBL397852 | 0.71 | CFTR (0.66) | MAPTALDH1A1MEN1KMT2AROCK1 | |
| SCHEMBL22754943 | 0.71 | MEN1 (0.43) | PDE10AMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL22729551 | 0.71 | MAPT (0.51) | PDE10AMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL22754851 | 0.69 | RAB9A (0.52) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL22729668 | 0.66 | PDE10A (0.47) | PDE10AMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL13043206 | 0.65 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |