Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755207 | 0.79 | HPGD (0.51) | TP53ALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL22729508 | 0.74 | MAPT (0.54) | RAB9APKMNPC1TP53MAPK1 | |
| SCHEMBL22729759 | 0.74 | PKM (0.51) | RAB9APKMNPC1TP53MAPK1 | |
| SCHEMBL13043227 | 0.74 | MAPT (0.52) | RAB9APKMNPC1TP53MAPK1 | |
| SCHEMBL22755067 | 0.74 | MDM4 (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL397852 | 0.72 | CFTR (0.66) | MAPTALDH1A1ROCK1CYP1A2CYP3A4 | |
| SCHEMBL10063184 | 0.72 | ITK (0.83) | RAB9ANPC1TP53MAPTSMN1; SMN2 | |
| SCHEMBL22754962 | 0.71 | MAPT (0.46) | RAB9APKMNPC1TP53MAPK1 | |
| SCHEMBL22755341 | 0.71 | MAPT (0.45) | RAB9APKMNPC1TP53MAPK1 | |
| SCHEMBL22755172 | 0.71 | GPR55 (0.56) | RAB9APKMNPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |