Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755167 | 0.94 | HRH1 (0.45) | HRH1CCR3KDM1ASPRBTK | |
| SCHEMBL22755080 | 0.92 | HRH1 (0.48) | HRH1CCR3SPRBTKKMT2A | |
| SCHEMBL22755095 | 0.92 | MLNR (0.44) | HRH1CCR3SPRBTKCCR5 | |
| SCHEMBL22754984 | 0.89 | LIPE (0.45) | HRH1CCR3KDM1ASPRALDH1A1 | |
| SCHEMBL22754940 | 0.89 | HRH1 (0.42) | HRH1CCR3SPR | |
| SCHEMBL22755114 | 0.89 | HRH1 (0.46) | HRH1CCR3KDM1ASPRBTK | |
| SCHEMBL22755349 | 0.87 | HRH1 (0.61) | HRH1CCR3 | |
| SCHEMBL22755321 | 0.85 | HRH1 (0.41) | HRH1CCR3KDM1ASPRBTK | |
| SCHEMBL22755319 | 0.83 | EPHX2 (0.43) | HRH1CCR3KMT2AALDH1A1HPGD | |
| SCHEMBL22754968 | 0.81 | BTK (0.47) | SPRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |