Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754984 | 0.91 | LIPE (0.45) | HRH1CCR3MMP13MMP2FPR2 | |
| SCHEMBL22755095 | 0.89 | MLNR (0.44) | HRH1CCR3KCNH2HSD11B1SPR | |
| SCHEMBL22755167 | 0.89 | HRH1 (0.45) | HRH1CCR3EPHX2SPR | |
| SCHEMBL22755137 | 0.89 | HRH1 (0.45) | HRH1CCR3SPR | |
| SCHEMBL22755080 | 0.87 | HRH1 (0.48) | HRH1CCR3FPR2PROKR1EPHX2 | |
| SCHEMBL22755075 | 0.85 | ALDH1A1 (0.37) | HRH1CCR3SPR | |
| SCHEMBL22755349 | 0.83 | HRH1 (0.61) | HRH1CCR3KCNH2 | |
| SCHEMBL22755114 | 0.81 | HRH1 (0.46) | HRH1CCR3SPR | |
| SCHEMBL22755321 | 0.79 | HRH1 (0.41) | HRH1CCR3EPHX2HSD11B1SPR | |
| SCHEMBL22755319 | 0.79 | EPHX2 (0.43) | HRH1CCR3EPHX2HSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |