Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CBL | P22681 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755289 | 0.90 | MGLL (0.37) | MGLLDRD2DRD3KCNH2CBL | |
| SCHEMBL22754986 | 0.89 | MGLL (0.37) | MGLLDRD2DRD3KCNH2 | |
| SCHEMBL22755287 | 0.89 | MGLL (0.38) | MGLLGRIN2BMEN1KMT2A | |
| SCHEMBL22755233 | 0.88 | MGLL (0.33) | MGLL | |
| SCHEMBL22754903 | 0.88 | MGLL (0.37) | MGLLTP53MAPTCNR2DRD2 | |
| SCHEMBL29839356 | 0.88 | MGLL (0.44) | MGLLTP53MAPTDRD2DRD3 | |
| SCHEMBL22729616 | 0.88 | MGLL (0.44) | MGLLTP53MAPTDRD2DRD3 | |
| SCHEMBL22755344 | 0.84 | MGLL (0.47) | MGLLKCNH2 | |
| SCHEMBL22755282 | 0.84 | DRD3 (0.34) | MGLLTP53MAPTDRD3KCNH2 | |
| SCHEMBL22755304 | 0.83 | MGLL (0.40) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |