Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CBL | P22681 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755217 | 0.90 | MGLL (0.43) | MGLLDRD2DRD3KCNH2CBL | |
| SCHEMBL22754986 | 0.89 | MGLL (0.37) | MGLLDRD2DRD3KCNH2 | |
| SCHEMBL22755287 | 0.88 | MGLL (0.38) | MGLL | |
| SCHEMBL29839347 | 0.88 | MGLL (0.39) | MGLLDRD2DRD3KCNH2PDE2A | |
| SCHEMBL22729652 | 0.88 | MGLL (0.39) | MGLLDRD2DRD3KCNH2PDE2A | |
| SCHEMBL22754903 | 0.87 | MGLL (0.37) | MGLLDRD2DRD3KCNH2 | |
| SCHEMBL22754885 | 0.85 | HCRTR1 (0.35) | MGLLSLC6A9 | |
| SCHEMBL22755344 | 0.84 | MGLL (0.47) | MGLLKCNH2 | |
| SCHEMBL22755032 | 0.83 | MGLL (0.40) | MGLLDRD2DRD3KCNH2 | |
| SCHEMBL22755304 | 0.83 | MGLL (0.40) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |