Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755172 | 0.89 | GPR55 (0.56) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL22755207 | 0.82 | HPGD (0.51) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11779160 | 0.79 | KMT2A (0.63) | MEN1KMT2ANR1H4LRRK2PDK1 | |
| SCHEMBL20704909 | 0.76 | CFTR (0.65) | NR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL22647160 | 0.76 | MEN1 (0.55) | MEN1KMT2ANR1H4LRRK2PDK1 | |
| SCHEMBL22754848 | 0.74 | KDM4E (0.55) | MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5249717 | 0.73 | NR1H4 (0.65) | MEN1KMT2ANR1H4PDK1PDK2 | |
| SCHEMBL22755205 | 0.73 | NPC1 (0.46) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL11550139 | 0.73 | NR1H4 (0.81) | MEN1KMT2ANR1H4NPC1RAB9A | |
| SCHEMBL22755173 | 0.72 | GPR55 (0.53) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |