Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CFTR | P13569 | 3/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755172 | 0.84 | GPR55 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22755239 | 0.82 | MEN1 (0.50) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22754848 | 0.81 | KDM4E (0.55) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22755242 | 0.80 | KMT2A (0.57) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22754851 | 0.79 | RAB9A (0.52) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL22755015 | 0.78 | ITK (0.34) | HPGDCFTRBCAT2BLMALDH1A1 | |
| SCHEMBL22755205 | 0.78 | NPC1 (0.46) | MEN1KMT2AALDH1A1KDM4ETP53 | |
| SCHEMBL22755022 | 0.77 | LIPG (0.40) | — | |
| SCHEMBL22754915 | 0.76 | POLB (0.45) | HPGDKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3249869 | 0.74 | CFTR (0.60) | CFTRMEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |