Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.52 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 8/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729758 | 0.85 | PROKR1 (0.53) | PROKR1FASNMGLLCCNCCDK8 | |
| SCHEMBL22755307 | 0.83 | FASN (0.48) | PROKR1FASNMGLLCCNCCDK8 | |
| SCHEMBL22729440 | 0.79 | PROKR1 (0.44) | PROKR1FASNMGLLAVPR1A | |
| SCHEMBL22755134 | 0.77 | AVPR1A (0.49) | PROKR1FASNMGLLEIF4A3AVPR1A | |
| SCHEMBL22754995 | 0.75 | ALDH1A1 (0.41) | LMNATP53 | |
| SCHEMBL22729425 | 0.75 | TP53 (0.47) | MGLLLMNATP53 | |
| SCHEMBL22755044 | 0.75 | SCD (0.44) | MGLL | |
| SCHEMBL22755323 | 0.74 | SPR (0.38) | PROKR1TP53 | |
| SCHEMBL22755079 | 0.74 | SPR (0.46) | LMNA | |
| SCHEMBL22754900 | 0.73 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |