Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233407 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBCASP3ALDH1A1KDM4E | |
| SCHEMBL24633637 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBCASP3ALDH1A1KDM4E | |
| SCHEMBL30204261 | 0.83 | LMNA (0.57) | SMN1; SMN2POLBALDH1A1SMYD3LMNA | |
| SCHEMBL19329581 | 0.83 | LMNA (0.57) | SMN1; SMN2POLBALDH1A1SMYD3LMNA | |
| SCHEMBL30168113 | 0.82 | NOTUM (0.55) | SMN1; SMN2POLBCASP3ALDH1A1KDM4E | |
| SCHEMBL2572591 | 0.82 | NOTUM (0.55) | SMN1; SMN2POLBCASP3ALDH1A1KDM4E | |
| SCHEMBL27801761 | 0.81 | KDM4E (0.47) | SMN1; SMN2POLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27570035 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBCASP3ALDH1A1KDM4E | |
| Acetic Acid SCHEMBL22437596 | 0.80 | NOTUM (0.52) | SMN1; SMN2POLBCASP3ALDH1A1KDM4E | |
| SCHEMBL22757190 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBCASP3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | disclosed |
| EP-3747864-A1 | A METHOD FOR PREPARING METHYL (Z)-3-[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE)-OXINDOLE-6-CARBOXYLATE (INTEDANIB, NINTEDANIB) | ZENTIVA, K.S. (CZ) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | CYP8B1, HSD11B1, HSD11B2 | SMN1; SMN2 3552/4885POLB 1779/4885CASP3 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.