Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342122 | 0.96 | THRB (0.33) | THRBLMNATDP1ALDH1A1 | |
| SCHEMBL21342068 | 0.82 | — | — | |
| SCHEMBL20161711 | 0.76 | BCHE (0.43) | LMNAALDH1A1 | |
| SCHEMBL16994826 | 0.75 | THRB (0.32) | THRBLMNATDP1 | |
| SCHEMBL3294716 | 0.75 | THRB (0.32) | THRBLMNATDP1 | |
| SCHEMBL10015241 | 0.75 | THRB (0.32) | THRBLMNATDP1 | |
| SCHEMBL30057341 | 0.75 | THRB (0.32) | THRBLMNATDP1 | |
| SCHEMBL1900467 | 0.75 | THRB (0.32) | THRBLMNATDP1 | |
| SCHEMBL1900465 | 0.75 | THRB (0.32) | THRBLMNATDP1 | |
| SCHEMBL28627915 | 0.75 | THRB (0.32) | THRBLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |