Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354194 | 1.00 | CHRNB2 (0.31) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL22757355 | 1.00 | CHRNB2 (0.31) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL19550793 | 0.81 | ALDH1A1 (0.33) | POLB | |
| SCHEMBL19550906 | 0.81 | ALDH1A1 (0.33) | POLB | |
| SCHEMBL19550926 | 0.81 | ALDH1A1 (0.33) | POLB | |
| SCHEMBL22757443 | 0.75 | CHRNB2 (0.33) | CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3 | |
| SCHEMBL354629 | 0.75 | — | — | |
| SCHEMBL354628 | 0.75 | — | — | |
| SCHEMBL6632497 | 0.75 | — | — | |
| SCHEMBL21989636 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |