Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 16/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757471 | 0.80 | ADORA3 (0.41) | ADORA1ADORA3ADORA2AADORA2BADRA2A | |
| SCHEMBL22750600 | 0.78 | ADORA3 (0.48) | ADORA1ADORA3ADORA2AADORA2BADRA2A | |
| SCHEMBL22757421 | 0.70 | ADORA3 (0.55) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL22757465 | 0.70 | ADORA3 (0.39) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL22757323 | 0.69 | ADORA1 (0.47) | ADORA1ADORA3ADORA2AADORA2BADRA2A | |
| SCHEMBL22757354 | 0.68 | ADORA1 (0.48) | ADORA1ADORA3ADORA2AADORA2BADRA2A | |
| SCHEMBL22757464 | 0.68 | ADORA3 (0.41) | ADORA1ADORA3ADORA2A | |
| SCHEMBL22757500 | 0.67 | ADORA3 (0.55) | ADORA1ADORA3ADORA2AADORA2BTMIGD3 | |
| SCHEMBL22750499 | 0.67 | ADORA1 (0.55) | ADORA1ADORA3ADORA2AADORA2BADRA2A | |
| SCHEMBL14468261 | 0.66 | ADORA2A (0.56) | ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |