Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 8/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396358 | 0.89 | ABCB1 (0.45) | ABCB1MAPTGPR35KDM4EGAA | |
| SCHEMBL28953326 | 0.81 | GPR35 (0.48) | ABCB1MAPTGPR35KDM4EGAA | |
| SCHEMBL28898896 | 0.81 | MAPT (0.47) | ABCB1MAPTKDM4EGAALMNA | |
| SCHEMBL28844792 | 0.81 | MAPT (0.44) | ABCB1MAPTGPR35KDM4EGAA | |
| SCHEMBL215255 | 0.80 | MAPT (0.43) | MAPTGPR35KDM4EGAALMNA | |
| SCHEMBL215256 | 0.80 | MAPT (0.43) | MAPTGPR35KDM4EGAALMNA | |
| SCHEMBL2735962 | 0.80 | MAPT (0.43) | MAPTGPR35KDM4EGAALMNA | |
| SCHEMBL28844618 | 0.79 | MAPT (0.44) | ABCB1MAPTGPR35KDM4EGAA | |
| SCHEMBL5356050 | 0.79 | KMT2A (0.52) | ABCB1MAPTKDM4EGAALMNA | |
| SCHEMBL29865413 | 0.79 | MAPT (0.44) | ABCB1MAPTGPR35KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |