Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760185 | 0.95 | HPGD (0.43) | LMNAMAPTDGAT1SOAT1PIK3CA | |
| SCHEMBL22747893 | 0.93 | MAPK1 (0.39) | LMNAMAPTSMN1; SMN2KDM4EPIK3CA | |
| SCHEMBL22748357 | 0.92 | JMJD6 (0.39) | LMNAMAPTSMN1; SMN2KDM4EDGAT1 | |
| SCHEMBL22748253 | 0.91 | HSD17B10 (0.39) | LMNAMAPTSMN1; SMN2KDM4EPIK3CA | |
| SCHEMBL22760192 | 0.91 | ALDH1A1 (0.41) | LMNAMAPTKDM4EDGAT1SOAT1 | |
| SCHEMBL22747825 | 0.91 | HPGD (0.45) | LMNAMAPTSMN1; SMN2TP53MAPK1 | |
| SCHEMBL22747823 | 0.91 | ALDH1A1 (0.45) | LMNAMAPTKDM4EDGAT1SOAT1 | |
| SCHEMBL22748239 | 0.91 | HSD17B10 (0.41) | LMNAKDM4EPIK3CAHSD17B10TP53 | |
| SCHEMBL22760193 | 0.90 | ALDH1A1 (0.45) | LMNAMAPTKDM4EPIK3CAHSD17B10 | |
| SCHEMBL22747889 | 0.90 | HSD17B10 (0.39) | LMNAMAPTSMN1; SMN2KDM4EDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |