Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760185 | 0.93 | HPGD (0.43) | ALDH1A1MAPTMAPK1DGAT1SOAT1 | |
| SCHEMBL22748239 | 0.92 | HSD17B10 (0.41) | ALDH1A1MAPK1HPGDHSD17B10ALOX15 | |
| SCHEMBL22747893 | 0.91 | MAPK1 (0.39) | ALDH1A1MAPTMAPK1HPGDHSD17B10 | |
| SCHEMBL22760232 | 0.91 | HPGD (0.44) | ALDH1A1MAPTMAPK1HPGDHSD17B10 | |
| SCHEMBL22760149 | 0.91 | LMNA (0.41) | ALDH1A1MAPTMAPK1DGAT1SOAT1 | |
| SCHEMBL22748357 | 0.91 | JMJD6 (0.39) | ALDH1A1MAPTMAPK1DGAT1SOAT1 | |
| SCHEMBL22747831 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1DGAT1SOAT1 | |
| SCHEMBL22748253 | 0.90 | HSD17B10 (0.39) | ALDH1A1MAPTMAPK1HPGDHSD17B10 | |
| SCHEMBL22747823 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1DGAT1SOAT1 | |
| SCHEMBL22748196 | 0.89 | EDNRA (0.42) | ALDH1A1MAPTMAPK1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |