Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760094 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22747883 | 0.83 | MAPT (0.50) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22760172 | 0.81 | MAPT (0.47) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22760543 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22760129 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22760095 | 0.75 | MAPT (0.48) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22760162 | 0.74 | TSHR (0.47) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22760544 | 0.74 | MEN1 (0.53) | ALDH1A1MAPTGAAKDM4ETHRB | |
| SCHEMBL22748263 | 0.73 | MAPK8 (0.40) | ALDH1A1MAPTGAAKDM4EHPGD | |
| SCHEMBL22760117 | 0.71 | FOLH1 (0.36) | ALDH1A1MAPTGAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |