Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760122 | 0.92 | MAPT (0.49) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22760194 | 0.91 | MAPT (0.49) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22760494 | 0.91 | MAPT (0.49) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22760136 | 0.89 | NPSR1 (0.59) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22747833 | 0.89 | FOLH1 (0.41) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22760195 | 0.88 | MAPT (0.49) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22760465 | 0.83 | CYP2A13 (0.40) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22760486 | 0.80 | FOLH1 (0.43) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22748283 | 0.79 | FOLH1 (0.42) | MAPTNPSR1ALDH1A1LMNAGAA | |
| SCHEMBL22748245 | 0.79 | FOLH1 (0.42) | MAPTNPSR1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |