Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | POLA1 | P09884 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22765433 | 0.95 | PDE4D (0.58) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| Gemcitabine Elaidate SCHEMBL582036 | 0.90 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| Gemcitabine Elaidate SCHEMBL26225695 | 0.90 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| Gemcitabine Elaidate SCHEMBL582035 | 0.90 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| Gemcitabine Elaidate SCHEMBL582034 | 0.90 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| Gemcitabine Elaidate SCHEMBL14460099 | 0.90 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| SCHEMBL21849051 | 0.89 | PDE4D (0.63) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| SCHEMBL4931963 | 0.88 | PDE3A (0.62) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| SCHEMBL15197943 | 0.88 | PDE4D (0.62) | PDE4DPDE3ASLC29A1POLA1ITGB3 | |
| SCHEMBL16366570 | 0.88 | POLA1 (0.52) | PDE4DPDE3ASLC29A1POLA1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200384007-A1 | LIPID NANOPARTICLES CONTAINING PHARMACEUTICAL AND/OR NUTRACEUTICAL AGENTS AND METHODS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2020-12-10 | — | — | US | disclosed |
| WO-2020247912-A1 | LIPID NANOPARTICLES CONTAINING PHARMACEUTICAL AND/OR NUTRACEUTICAL AGENTS AND METHODS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200384007-A1 | LIPID NANOPARTICLES CONTAINING PHARMACEUTICAL AND/OR NUTRACEUTICAL AGENTS AND METHODS THEREOF | GSTO1, LIPC, PHOSPHO1 | PDE4D 1843/4885PDE3A 1985/4885SLC29A1 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.