Validamycin A

Validamycin A

SCHEMBL22761

OCC1=CC(NC2CC(CO)C(OC3OC(CO)C(O)C(O)C3O)C(O)C2O)C(O)C(O)C1O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AMY2A P04746 8/20 0.56
MGAM O43451 6/20 0.56
SI P14410 5/20 0.56
GAA P10253 4/20 0.56
AMY1A P0DUB6 3/20 0.56
CNR1 P21554 1/20 0.56
PTGS1 P23219 1/20 0.56
PDE4A P27815 1/20 0.56
PDE3A Q14432 1/20 0.56
MGAM2 Q2M2H8 1/20 0.56
ALDH1A1 P00352 1/20 0.56
GLA P06280 1/20 0.56
TREH O43280 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Validamycin A SCHEMBL29451180 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL14409005 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL8819801 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL19231832 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL14408710 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL15906030 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin SCHEMBL3121491 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL10033386 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL16028080 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A
Validamycin A SCHEMBL14408718 1.00 AMY2A (0.56) AMY2AMGAMSIGAAAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16799 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
CN-122030410-A Sterilization composition containing penoxsulam and validamycin as well as preparation method and application thereof 江苏丰登作物保护股份有限公司 2026-05-15 CN claimed
US-12582121-B2 Synergistic fungicidal composition JDM SCIENT RESEARCH ORGANISATION PRIVATE LIMITED (IN) 2026-03-24 US claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20260068884-A1 COMPOSITION USED FOR KILLING FUNGI AND METHOD FOR APPLYING COMPOSITION JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) 2026-03-12 US claimed
CN-121569819-A Penconazole and well containing chlorine fluoride composition of validamycin and application thereof 蚌埠格润生物科技有限公司 2026-02-27 CN claimed
WO-2026042101-A1 PESTICIDAL COMPOSITION CONTAINING IPROBENFOS JU AGRI SCIENCES PRIVATE LIMITED (IN) 2026-02-26 WO claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-0642502-B1 FUNGICIDAL IMIDAZOLINONES DU PONT (US) 2000-07-12 EP claimed
CN-1051205-C Composition for treatment of bacterial wilt TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2000-04-12 CN claimed
CN-1244342-A Fungicidal composition for rice crop and method for controlling disease of rice crop NIHON NOHYAKU CO LTD (JP) 2000-02-16 CN claimed
WO-1999011129-A1 ENANTIOMERICALLY ENRICHED COMPOSITIONS AND THEIR PESTICIDAL USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-11 WO claimed
CN-1165656-A High effect mycin powder injection ZHANG BO (CN) 1997-11-26 CN claimed
US-5169767-A Culture product of Sclerotium promoted by validamycin TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-08 US claimed
EP-0199591-B1 VALIOLAMINE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1990-11-07 EP claimed
EP-0199591-A2 Valiolamine derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1986-10-29 EP claimed
US-4089947-A FOR CONTROLLING FUNGAL PLANT DISEASES TAKEDA CHEMICAL INDUSTRIES LTD. (JA) 1978-05-16 US claimed
US-4011391-A VALIDAMYCIN C, D, E AND F ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-03-08 US claimed