Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348434 | 0.66 | GSK3A (0.44) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL15122509 | 0.64 | TDP1 (0.44) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL24282303 | 0.64 | TDP1 (0.44) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL15122510 | 0.64 | TDP1 (0.44) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL7456326 | 0.64 | ABL1 (0.51) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL22511412 | 0.63 | LMNA (0.47) | GSK3AGSK3BABL1RIN1TDP1 | |
| SCHEMBL9662940 | 0.63 | GSK3A (0.47) | GSK3AGSK3BALDH1A1PIN1PIN4 | |
| SCHEMBL3384734 | 0.63 | GSK3A (1.00) | GSK3AGSK3BALDH1A1PIN1PIN4 | |
| SCHEMBL3582727 | 0.61 | GSK3A (0.50) | GSK3AGSK3BALDH1A1PIN1PIN4 | |
| SCHEMBL23511651 | 0.61 | ABL1 (0.45) | GSK3AGSK3BABL1RIN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247782-A1 | NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF | AVIDITY BIOSCIENCES, INC. (US) | 2020-12-10 | — | — | WO | disclosed |