Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206520 | 0.91 | PRKCA (0.61) | PRKCAMMP12HTR2CSLC6A4NR1I2 | |
| SCHEMBL2277223 | 0.89 | PRKCA (0.47) | PRKCAMMP12NR1I2 | |
| SCHEMBL2276303 | 0.85 | PRKCA (0.53) | PRKCAMMP12HTR2CSLC6A4NR1I2 | |
| SCHEMBL2273255 | 0.84 | PRKCA (0.54) | PRKCAMMP12NR1I2 | |
| SCHEMBL2271497 | 0.82 | PRKCA (0.60) | PRKCAMMP12NR1I2 | |
| SCHEMBL2277015 | 0.81 | PRKCA (0.53) | PRKCAMMP12NR1I2 | |
| SCHEMBL2275104 | 0.81 | PRKCA (0.53) | PRKCAMMP12NR1I2 | |
| SCHEMBL2275227 | 0.81 | PRKCA (0.47) | PRKCAMMP12NR1I2 | |
| SCHEMBL2276697 | 0.81 | PRKCA (0.52) | PRKCAMMP12NR1I2 | |
| SCHEMBL2278806 | 0.80 | PRKCA (0.56) | PRKCAMMP12NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989438-B2 | Therapeutic compounds | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-02 | — | — | US | disclosed |