Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.66 |
| ▸ | CA2 | P00918 | 7/20 | 0.66 |
| ▸ | STAT3 | P40763 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.54 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19199071 | 0.85 | CA1 (0.68) | CA1CA2STAT3NPC1RAB9A | |
| SCHEMBL8912404 | 0.83 | MEN1 (0.69) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL17465708 | 0.80 | MAPT (0.65) | NPC1RAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL15613254 | 0.80 | MAPT (0.54) | CA1CA2STAT3NPC1RAB9A | |
| SCHEMBL21623325 | 0.80 | CA2 (0.61) | CA1CA2STAT3NPC1RAB9A | |
| SCHEMBL28261080 | 0.78 | CA1 (0.73) | CA1CA2STAT3NPC1RAB9A | |
| SCHEMBL20779489 | 0.78 | MAPT (0.52) | MAPTMEN1ALDH1A1LMNAMAPK1 | |
| SCHEMBL14372417 | 0.78 | CA1 (0.65) | CA1CA2STAT3NPC1RAB9A | |
| SCHEMBL21623209 | 0.77 | CYP1A2 (0.54) | CA1CA2STAT3NPC1RAB9A | |
| SCHEMBL21623225 | 0.77 | CA2 (0.57) | CA1CA2STAT3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247575-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2020-12-10 | — | — | WO | disclosed |