SCHEMBL22765983

Nc1ccn([C@H]2CC(OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)CC3OP(=O)(O)OC[C@@H]3CC[C@H](n4cnc5c(N)ncnc54)O3)[C@@H](COP(=O)(O)OC3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.48

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	TERT	O14746	1/20	0.48

▸	P2RY2	P41231	1/20	0.48

▸	P2RY4	P51582	1/20	0.48

▸	P2RY6	Q15077	1/20	0.48

▸	POLB	P06746	1/20	0.47

▸	RNASEL	Q05823	2/20	0.47

▸	FUT5	Q11128	1/20	0.46

▸	F2	P00734	1/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22765945	1.00	TERT (0.48)	TERTP2RY2P2RY4P2RY6POLB
SCHEMBL16574745	0.94	RNASEL (0.49)	POLBRNASEL
SCHEMBL21895950	0.94	RNASEL (0.49)	POLBRNASEL
SCHEMBL20324868	0.94	TERT (0.53)	TERTP2RY2P2RY4P2RY6POLB
SCHEMBL21540009	0.94	TERT (0.53)	TERTP2RY2P2RY4P2RY6POLB
SCHEMBL20325223	0.94	TERT (0.53)	TERTP2RY2P2RY4P2RY6POLB
SCHEMBL20782764	0.94	TERT (0.53)	TERTP2RY2P2RY4P2RY6POLB
SCHEMBL17948732	0.94	RNASEL (0.49)	POLBRNASEL
SCHEMBL30839331	0.92	P2RY2 (0.57)	TERTP2RY2P2RY4P2RY6POLB
SCHEMBL18822882	0.89	TERT (0.52)	TERTP2RY2P2RY4P2RY6POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020246443-A1	PRODUCTION METHOD FOR BIFURCATED LIPID-LINKED OLIGONUCLEOTIDE, AND INTERMEDIATE	塩野義製薬株式会社	2020-12-10	—	—	WO	disclosed