Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22768040 | 0.78 | ALDH1A1 (0.39) | KMT2AMEN1TSHRALDH1A1CSNK1D | |
| SCHEMBL4833839 | 0.78 | KMT2A (0.46) | KMT2AMEN1CSNK1DCSNK1EPTGS2 | |
| SCHEMBL2528673 | 0.78 | ALDH1A1 (0.40) | TSHRALDH1A1CSNK1DLMNAMAPT | |
| SCHEMBL20213765 | 0.78 | PTPN1 (0.40) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL24194907 | 0.72 | MPO (0.49) | KMT2AMEN1TSHRALDH1A1LMNA | |
| SCHEMBL24190578 | 0.71 | MPO (0.44) | KMT2AMEN1TSHRALDH1A1CSNK1D | |
| SCHEMBL8824404 | 0.67 | CSF1R (0.46) | KMT2AMEN1ALDH1A1CSNK1DCSNK1E | |
| SCHEMBL17183581 | 0.67 | AKR1C3 (0.39) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL24194269 | 0.66 | MEN1 (0.39) | KMT2AMEN1TSHRALDH1A1CSNK1D | |
| SCHEMBL31486896 | 0.66 | HTT (0.43) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247447-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES, COMPOSITIONS AND METHODS AS OREXIN ANTAGONISTS | HAGER BIOSCIENCES, LLC (US) | 2020-12-10 | — | — | WO | disclosed |