Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254943 | 0.87 | CA12 (0.49) | LMNASMN1; SMN2ADORA2AADORA1KMT2A | |
| SCHEMBL12442229 | 0.86 | NPC1 (0.52) | LMNASMN1; SMN2KMT2AMAPTPOLB | |
| SCHEMBL2043767 | 0.86 | TP53 (0.55) | PDE4DLMNACYP3A4ADORA2AADORA1 | |
| SCHEMBL1999421 | 0.78 | SMN1; SMN2 (0.48) | PDE4DCYP1A2SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL25170232 | 0.77 | NPC1 (0.48) | PDE4DADORA2AADORA1KMT2AMAPT | |
| SCHEMBL15019791 | 0.77 | ALDH1A1 (0.53) | LMNASMN1; SMN2ADORA1KMT2AKDM4E | |
| SCHEMBL20574684 | 0.76 | S1PR1 (0.42) | KMT2AMAPTKDM4EALDH1A1HTT | |
| SCHEMBL30444564 | 0.76 | S1PR1 (0.42) | KMT2AMAPTKDM4EALDH1A1HTT | |
| SCHEMBL16242012 | 0.75 | TP53 (0.39) | LMNASMN1; SMN2KMT2AALDH1A1RAB9A | |
| SCHEMBL9300651 | 0.74 | PDE4D (0.59) | PDE4DLMNACYP1A2CYP3A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981772-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-04-13 | — | — | EP | disclosed |
| WO-2020246602-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | 大塚製薬株式会社 | 2020-12-10 | — | — | WO | disclosed |