Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13643084 | 0.87 | F2 (0.43) | RAB9AMAPTCXCR1CXCR2NPC1 | |
| SCHEMBL7710947 | 0.85 | ESR1 (0.53) | MAPTSMN1; SMN2ESR1ESR2TSHR | |
| SCHEMBL19479754 | 0.85 | ESR1 (0.53) | MAPTSMN1; SMN2ESR1ESR2TSHR | |
| SCHEMBL10509525 | 0.83 | NPC1 (0.51) | RAB9ANPC1ALDH1A1LMNACYP2C9 | |
| SCHEMBL22768597 | 0.81 | MAPT (0.46) | RAB9AMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2060365 | 0.79 | CYP4F2 (0.59) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13643085 | 0.78 | KMT2A (0.50) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL22256182 | 0.78 | HTR2A (0.51) | RAB9ASMN1; SMN2HTR2AMEN1KMT2A | |
| SCHEMBL8233788 | 0.76 | PTPRB (0.56) | RAB9AACACBCXCR1CXCR2SMN1; SMN2 | |
| SCHEMBL13802839 | 0.76 | RAB9A (0.56) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220130-A1 | NOVEL BORONIC ESTERS AND METHODS FOR MAKING THE SAME | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-07-14 | — | — | US | disclosed |
| US-20200385410-A1 | NOVEL BORONIC ESTERS AND METHODS FOR MAKING THE SAME | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220130-A1 | NOVEL BORONIC ESTERS AND METHODS FOR MAKING THE SAME | CD79B, BLVRB, BCL6 | RAB9A 1258/4885MAPT 4066/4885ACACB 2574/4885 |
| US-20200385410-A1 | NOVEL BORONIC ESTERS AND METHODS FOR MAKING THE SAME | CD79B, BLVRB, BCL6 | RAB9A 1258/4885MAPT 4066/4885ACACB 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.