Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2277112 | 1.00 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL14062519 | 0.77 | — | — | |
| SCHEMBL5500536 | 0.77 | — | — | |
| SCHEMBL22947098 | 0.73 | — | — | |
| SCHEMBL5487957 | 0.70 | MEN1 (0.52) | ALDH1A1SMN1; SMN2KDM4EKMT2AMAPT | |
| SCHEMBL11103862 | 0.70 | MEN1 (0.52) | ALDH1A1SMN1; SMN2KDM4EKMT2AMAPT | |
| SCHEMBL11107953 | 0.70 | MEN1 (0.52) | ALDH1A1SMN1; SMN2KDM4EKMT2AMAPT | |
| SCHEMBL441370 | 0.69 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KDM4EKMT2AMAPT | |
| SCHEMBL16547018 | 0.69 | L3MBTL1 (0.35) | L3MBTL1GAAKDM4EKMT2AMAPT | |
| SCHEMBL1752174 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998462-B2 | Linkers for anchoring targeting ligands | KEREOS, INC. (US) | 2011-08-16 | — | — | US | disclosed |
| US-5552427-A | ANTITUMOR AGENTS AND ANTICARCINOGENIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0656210-A1 | Imidazole derivatives as glutaminose inhibitors | Takeda Chemical Industries, Ltd. (JP) | 1995-06-07 | — | — | EP | disclosed |