SCHEMBL227734

SCHEMBL227734

[CH2]CCCCCCCCCCOC(=O)C(=C)C

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.71
POLB P06746 1/20 0.53
APEX1 P27695 1/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
THRB P10828 1/20 0.52
ALDH1A1 P00352 4/20 0.40
CYP3A4 P08684 1/20 0.39
NAAA Q02083 1/20 0.36
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
EPHX1 P07099 1/20 0.34
ACHE P22303 4/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27459407 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9357929 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1228562 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL329015 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL10437170 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL33382 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1142983 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1228461 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL33312 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1228491 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114440-A EMULSION POLYMERIZING AN AQUEOUS SOLUTION OF A WATER-INSOLUBLE GROUP-BEARING SILICONE RESIN AND A VINYL SILANETRIOL MONOMER; COATED AND CURED INTO A FILM HAVING WEAR AND CHEMICAL RESISTANCE AND WATERPROOFING PROPERTIES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-09-05 US claimed
US-5973068-A BLEND OF WATER INSOLUBLE SILICONE RESIN AND VINYL MONOMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-10-26 US claimed
JP-1050888-A None JP disclosed
CN-112867640-B Coating composition, coated fabric, method of making coated fabric, and articles made from coated fabric 陶氏环球技术有限责任公司 2024-03-29 CN disclosed
WO-2024024613-A1 COATED ARTICLE AND PRODUCTION METHOD THEREFOR 信越化学工業株式会社 2024-02-01 WO disclosed
EP-3603607-B1 MULTIFUNCTIONAL MONOMER FOR DENTAL MATERIAL, AND HYDROXYL GROUP-CONTAINING MONOMER FOR DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2023-09-20 EP disclosed
WO-2023136337-A1 DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER クラレノリタケデンタル株式会社 2023-07-20 WO disclosed
US-20220001829-A1 A COATING COMPOSITION, A COATED FABRIC, A METHOD OF MAKING A COATED FABRIC, AND AN ARTICLE MADE FROM THE COATED FABRIC DOW SILICONES CORPORATION 2022-01-06 US disclosed
CN-112867640-A Coating composition, coated fabric, method of making coated fabric, and article made from coated fabric 陶氏环球技术有限责任公司 2021-05-28 CN disclosed
WO-2020122192-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2020-06-18 WO disclosed
EP-3603607-A1 MULTIFUNCTIONAL MONOMER FOR DENTAL MATERIAL, AND HYDROXYL GROUP-CONTAINING MONOMER FOR DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2020-02-05 EP disclosed
EP-0841355-A2 Silicone resin-containing emulsion compositions, methods for making them, and cured films thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-05-13 EP disclosed
EP-0460496-B1 Tetra-amino-anthraquinone dyes BASF AG (DE) 1994-11-30 EP disclosed
CN-1023699-C Difluoromethyl compounds MERCK PATENT GMBH (DE) 1994-02-09 CN disclosed
US-5151217-A Addition copolymerizable cationic surfactant for transparent solids IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-09-29 US disclosed
EP-0460496-A1 Tetra-amino-anthraquinone dyes BASF Aktiengesellschaft (DE) 1991-12-11 EP disclosed
EP-0449450-A1 Micro-emulsions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-02 EP disclosed
CN-1039797-A difluoromethyl compound MERCK PATENT GMBH (DE) 1990-02-21 CN disclosed
JP-S6450888-A NOVEL ORGANOSILICON COMPOUND KURARAY CO 1989-02-27 JP disclosed
JP-S06450888-A 0001-01-01 JP disclosed