SCHEMBL33382

SCHEMBL33382

[CH2]CCCCCCCOC(=O)C(=C)C

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.71
POLB P06746 1/20 0.53
APEX1 P27695 1/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
THRB P10828 1/20 0.52
ALDH1A1 P00352 4/20 0.40
CYP3A4 P08684 1/20 0.39
NAAA Q02083 1/20 0.36
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
EPHX1 P07099 1/20 0.34
ACHE P22303 4/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27459407 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9357929 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1228562 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL227734 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL329015 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL10437170 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1142983 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1228461 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL33312 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1228491 1.00 TSHR (0.71) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 701 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102076797-B Coating composition and coating film formation method using same SHOWA DENKO KK 2014-03-12 CN claimed
EP-2223946-B1 Modified natural rubber or modified natural rubber latex and rubber composition BRIDGESTONE CORP (JP) 2012-08-22 EP claimed
EP-2223946-A2 Modified natural rubber or modified natural rubber latex and rubber composition Bridgestone Corporation (JP) 2010-09-01 EP claimed
US-7517471-B2 And benzo[1,2-b:3,4-b']difuran derivatives; liquid crystal media, electrooptical displays; negative Delta epsilon, vertically alligned thin film transistors MERCK PATENT GMBH (DE) 2009-04-14 US claimed
EP-1629021-A4 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-03-25 EP claimed
US-7442419-B2 Comprising one or more dielectrically positive compounds having a dielectric anisotropy of more than 3; twisted Nematic (TN) or Plane Switching (IPS) type; low rotational viscosity; polycyclo cyclohexyl fluorocarbon benzyl ether derivatives, electrooptics MERCK PATENT GMBH (DE) 2008-10-28 US claimed
EP-1973587-A2 METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS Allaccem, Inc. (US) 2008-10-01 EP claimed
US-20070228327-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2007-10-04 US claimed
WO-2007070801-A2 METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS ALLACCEM, INC. (US) 2007-06-21 WO claimed
US-20070010610-A1 Modified natural rubber or modified natural rubber latex, and rubber composition and pneumatic tire BRIDGESTONE CORPORATION (JP) 2007-01-11 US claimed
EP-1629021-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2006-03-01 EP claimed
WO-2004106397-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2004-12-09 WO claimed
US-6326417-B1 CONTAINING SALICYLIC ACID COMPOUND AS MICROBIOCIDES JENERIC/PENTRON INCORPORATED 2001-12-04 US claimed
JP-1050887-A None JP disclosed
CN-118339216-A Silsesquioxane derivative, curable composition, hard coating agent, cured product, hard coating, and substrate 东亚合成株式会社 2024-07-12 CN disclosed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US disclosed
WO-1990001056-A1 DIFLUOROMETHYL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-02-08 WO disclosed
JP-S6450887-A ORGANOSILICON COMPOUND KURARAY CO 1989-02-27 JP disclosed
WO-1988010251-A1 ARYL SULPHUR PENTAFLUORIDES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-12-29 WO disclosed
JP-S06450887-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS TSHR 1186/4885POLB 1257/4885APEX1 166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.