Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459407 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9357929 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1228562 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL227734 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL329015 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10437170 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL33382 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1142983 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1228461 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1228491 | 1.00 | TSHR (0.71) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3415539-B1 | POLYMERIZABLE COMPOSITION AND KIT THEREOF, AND POLYMERIZATION INITIATOR | SUN MEDICAL CO LTD (JP) | 2022-03-30 | — | — | EP | claimed |
| EP-2578201-B1 | Dental materials with improved hydrolysis stability on the basis of phthalic acid monomers | IVOCLAR VIVADENT AG (LI) | 2020-11-25 | — | — | EP | claimed |
| EP-2716276-B1 | Kit and method for indirect chair-side production of composite inlays | VOCO GMBH (DE) | 2019-04-24 | — | — | EP | claimed |
| EP-3013874-B1 | ADDITIVE THAT IMPROVES ADHESION AND COATING COMPOUND CONTAINING THE SAME | BYK CHEMIE GMBH (DE) | 2016-12-14 | — | — | EP | claimed |
| EP-2047837-B1 | Dental adhesive and use thereof | KERR CORP (US) | 2016-04-13 | — | — | EP | claimed |
| EP-1968528-B1 | DENTAL COMPOSITIONS WITH SURFACE-TREATED FILLER FOR SHELF STABILITY | 3M INNOVATIVE PROPERTIES CO (US) | 2016-02-17 | — | — | EP | claimed |
| EP-1749513-B1 | Photopolymerisable dental material with bisacylphosphine oxides as initiator | IVOCLAR VIVADENT AG (LI) | 2009-03-04 | — | — | EP | claimed |
| EP-1973587-A2 | METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS | Allaccem, Inc. (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007070801-A2 | METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS | ALLACCEM, INC. (US) | 2007-06-21 | — | — | WO | claimed |
| EP-1508321-B1 | Dental adhesive composition | DENTSPLY SANKIN K K (JP) | 2007-05-23 | — | — | EP | claimed |
| US-6326417-B1 | CONTAINING SALICYLIC ACID COMPOUND AS MICROBIOCIDES | JENERIC/PENTRON INCORPORATED | 2001-12-04 | — | — | US | claimed |
| US-20240208990-A1 | SPIRO-COMPOUNDS AND COMPOSITIONS INCLUDING THE SAME | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2024-06-27 | — | — | US | disclosed |
| US-20240173211-A1 | DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT | SHOFU INC. (JP) | 2024-05-30 | — | — | US | disclosed |
| EP-4347602-A1 | SPIRO-COMPOUNDS AND COMPOSITIONS INCLUDING THE SAME | Solventum Intellectual Properties Company (US) | 2024-04-10 | — | — | EP | disclosed |
| EP-3604318-B1 | PHOSPHORUS-CONTAINING COMPOUND | MITSUI CHEMICALS INC (JP) | 2024-01-17 | — | — | EP | disclosed |
| EP-0460496-B1 | Tetra-amino-anthraquinone dyes | BASF AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| CN-1023699-C | Difluoromethyl compounds | MERCK PATENT GMBH (DE) | 1994-02-09 | — | — | CN | disclosed |
| US-5235096-A | Hydroxybenzenesulfone compound having a polymerizable group and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0460496-A1 | Tetra-amino-anthraquinone dyes | BASF Aktiengesellschaft (DE) | 1991-12-11 | — | — | EP | disclosed |
| CN-1039797-A | difluoromethyl compound | MERCK PATENT GMBH (DE) | 1990-02-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208990-A1 | SPIRO-COMPOUNDS AND COMPOSITIONS INCLUDING THE SAME | REN, PKD1, SAV1 | TSHR 988/4885POLB 3985/4885APEX1 2681/4885 |
| US-20240173211-A1 | DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT KIT | GRIK1, GRIN2B, GRIK2 | TSHR 2655/4885POLB 1327/4885APEX1 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.