Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2276652 | 0.91 | P2RX3 (0.62) | P2RX3P2RX2 | |
| SCHEMBL10244443 | 0.87 | P2RX3 (0.57) | P2RX3P2RX2 | |
| SCHEMBL2275247 | 0.87 | P2RX3 (0.53) | P2RX3P2RX2 | |
| SCHEMBL2274849 | 0.86 | P2RX3 (0.62) | P2RX3P2RX2 | |
| SCHEMBL2273728 | 0.86 | P2RX3 (0.58) | P2RX3P2RX2 | |
| SCHEMBL2275278 | 0.84 | P2RX3 (0.62) | P2RX3P2RX2 | |
| SCHEMBL2277572 | 0.84 | P2RX3 (0.41) | P2RX3P2RX2 | |
| SCHEMBL2273894 | 0.83 | P2RX3 (0.59) | P2RX3P2RX2 | |
| SCHEMBL2274696 | 0.83 | P2RX3 (0.59) | P2RX3P2RX2 | |
| SCHEMBL2272543 | 0.83 | P2RX3 (0.58) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989637-B2 | Triazole-substituted arylamides as P2X3 and P2X2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2011-08-02 | — | — | US | claimed |