SCHEMBL22776006

SCHEMBL22776006

CCS(=O)(=O)c1nn2c(-c3cccc(Cl)c3)ccnc2c1-c1nc2cc(C(F)(F)F)cnc2n1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.36
▸ BRAF P15056 4/20 0.35
▸ KDM4E B2RXH2 4/20 0.35
▸ PTGS2 P35354 2/20 0.35
▸ NPSR1 Q6W5P4 3/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.34
▸ GAA P10253 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ MET P08581 1/20 0.34
▸ PTGS1 P23219 1/20 0.33
▸ DYRK3 O43781 1/20 0.33
▸ DYRK1A Q13627 1/20 0.33
▸ DYRK2 Q92630 1/20 0.33
▸ DYRK1B Q9Y463 1/20 0.33
▸ GRIN1 Q05586 1/20 0.33
▸ GRIN2B Q13224 1/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22776106 0.94 POLB (0.38) POLBBRAFKDM4EPTGS2NPSR1
SCHEMBL29525381 0.93 KDM4E (0.42) POLBBRAFKDM4EDYRK3DYRK1A
SCHEMBL29525584 0.91 MAPT (0.37) POLBBRAFKDM4EPTGS2ALDH1A1
SCHEMBL29525341 0.91 NPSR1 (0.41) POLBKDM4ENPSR1NPC1ALDH1A1
SCHEMBL28684097 0.91 MAPT (0.41) POLBBRAFKDM4ENPSR1NPC1
SCHEMBL29525944 0.91 POLB (0.36) POLBKDM4EPTGS2NPSR1NPC1
SCHEMBL29526138 0.90 NPSR1 (0.37) POLBBRAFKDM4EPTGS2NPSR1
SCHEMBL29525360 0.89 POLB (0.39) POLBBRAFKDM4ENPSR1NPC1
SCHEMBL29525873 0.88 NPSR1 (0.36) POLBBRAFKDM4ENPSR1NPC1
SCHEMBL29525542 0.88 NPC1 (0.38) POLBKDM4ENPSR1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3983411-B1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD (IN) 2026-05-27 — — EP claimed
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents PI INDUSTRIES LTD (IN) 2025-08-12 — — US claimed
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2022-08-11 — — US claimed
EP-3983411-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI Industries Ltd. (IN) 2022-04-20 — — EP claimed
WO-2020250183-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2020-12-17 — — WO claimed
EP-3983411-B1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD (IN) 2026-05-27 — — EP disclosed
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents PI INDUSTRIES LTD (IN) 2025-08-12 — — US disclosed
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2022-08-11 — — US disclosed
EP-3983411-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI Industries Ltd. (IN) 2022-04-20 — — EP disclosed
WO-2020250183-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2020-12-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12384787-B2 Fused heterocyclic compounds and their use as pest control agents DDT, ACHE, KEAP1 POLB 4600/4885BRAF 649/4885KDM4E 160/4885
US-20220251094-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS DDT, ACHE, KEAP1 POLB 4600/4885BRAF 649/4885KDM4E 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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