SCHEMBL22777751

SCHEMBL22777751

CCCCn1c(CCl)nc2cc(Cl)ccc21

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.50
NUDT1 P36639 1/20 0.50
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
KMT2A Q03164 3/20 0.49
TP53 P04637 3/20 0.44
MAPT P10636 3/20 0.44
IRAK4 Q9NWZ3 1/20 0.44
TLR8 Q9NR97 2/20 0.44
TBXA2R P21731 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 2/20 0.43
USP2 O75604 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
THRB P10828 1/20 0.42
RECQL P46063 1/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22788758 0.85 BACE1 (0.47) BACE1NUDT1CNR1CNR2KMT2A
SCHEMBL23100636 0.84 BACE1 (0.63) BACE1NUDT1KMT2ATP53MAPT
SCHEMBL9979855 0.84 BACE1 (0.49) BACE1NUDT1CNR1CNR2KMT2A
Hydrochloric Acid SCHEMBL15301119 0.83 BACE1 (0.48) BACE1NUDT1CNR1CNR2KMT2A
SCHEMBL23100707 0.83 KMT2A (0.47) BACE1NUDT1KMT2ATP53MAPT
SCHEMBL11205958 0.83 MAPT (0.55) BACE1NUDT1CNR1CNR2KMT2A
SCHEMBL15415657 0.83 BACE1 (0.48) BACE1NUDT1KMT2ATBXA2R
SCHEMBL17194629 0.82 BACE1 (0.47) BACE1NUDT1KMT2ATP53MAPT
SCHEMBL15415539 0.82 BACE1 (0.47) BACE1NUDT1CNR1CNR2KMT2A
SCHEMBL28189725 0.82 BACE1 (0.47) BACE1NUDT1KMT2ATBXA2RMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230082611-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. 2023-03-16 US disclosed
EP-4028392-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2022-07-20 EP disclosed
CN-114728937-A Compositions and methods for treating respiratory syncytial virus 奇达拉治疗公司 2022-07-08 CN disclosed
CN-114390929-A Compositions and methods for treating respiratory syncytial virus 奇达拉治疗公司 2022-04-22 CN disclosed
EP-3982994-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2022-04-20 EP disclosed
WO-2021050612-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2021-03-18 WO disclosed
WO-2021050612-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2021-03-18 WO disclosed
WO-2020252396-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2020-12-17 WO disclosed
WO-2020252396-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS CIDARA THERAPEUTICS, INC. (US) 2020-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230082611-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS MDK, ALB, FCGR3B BACE1 2223/4885NUDT1 1952/4885CNR1 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.