Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 4/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19018767 | 1.00 | NT5E (0.39) | NT5EBACE1PDPK1MTORPTPN1 | |
| SCHEMBL19026639 | 0.92 | LGALS8 (0.38) | NT5EBACE1PDPK1MTORPTPN1 | |
| SCHEMBL19018840 | 0.92 | LGALS8 (0.38) | NT5EBACE1PDPK1MTORPTPN1 | |
| SCHEMBL19018766 | 0.92 | LGALS8 (0.38) | NT5EBACE1PDPK1MTORPTPN1 | |
| SCHEMBL12355204 | 0.85 | NT5E (0.38) | NT5EBACE1PTPN1PTPN2 | |
| SCHEMBL30128330 | 0.83 | BCHE (0.48) | BACE1PDPK1MTORPTPN1PTPN2 | |
| SCHEMBL10031484 | 0.82 | PDPK1 (0.38) | NT5EPDPK1MTORPTPN1PTPN2 | |
| SCHEMBL20854863 | 0.82 | PDPK1 (0.38) | NT5EPDPK1MTORPTPN1PTPN2 | |
| SCHEMBL8597607 | 0.82 | PDPK1 (0.38) | NT5EPDPK1MTORPTPN1PTPN2 | |
| SCHEMBL22181021 | 0.82 | PDPK1 (0.38) | NT5EPDPK1MTORPTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10864261-B2 | Synthetic vaccines against Streptococcus pneumoniae serotype 2 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10864261-B2 | Synthetic vaccines against Streptococcus pneumoniae serotype 2 | FUT5, SIGLEC7, ST6GAL1 | NT5E 2301/4885BACE1 3691/4885PDPK1 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.