Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776218 | 1.00 | TRPM8 (0.55) | TRPM8CHRM3KCNH2 | |
| SCHEMBL22776219 | 1.00 | TRPM8 (0.55) | TRPM8CHRM3KCNH2 | |
| SCHEMBL22784521 | 0.88 | CHRM3 (0.60) | TRPM8CHRM3KCNH2 | |
| Acetic Acid SCHEMBL29560775 | 0.84 | CHRM3 (0.56) | TRPM8CHRM3KCNH2 | |
| Acetic Acid SCHEMBL22776782 | 0.84 | CHRM3 (0.56) | TRPM8CHRM3KCNH2 | |
| SCHEMBL28686102 | 0.84 | CHRM3 (0.54) | TRPM8CHRM3KCNH2 | |
| SCHEMBL28686100 | 0.84 | CHRM3 (0.54) | TRPM8CHRM3KCNH2 | |
| SCHEMBL22784421 | 0.83 | CHRM3 (0.58) | TRPM8CHRM3KCNH2 | |
| SCHEMBL22784419 | 0.83 | CHRM3 (0.58) | TRPM8CHRM3KCNH2 | |
| SCHEMBL22784420 | 0.83 | CHRM3 (0.58) | TRPM8CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239892-A1 | COMPOUNDS FOR MODULATION OF CD68 AND USES THEREOF | ARKUDA THERAPEUTICS (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2020252222-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2020-12-17 | — | — | WO | disclosed |