Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 11/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28686100 | 1.00 | CHRM3 (0.54) | CHRM3TRPM8KCNH2HHAT | |
| SCHEMBL29561137 | 0.89 | CHRM3 (0.57) | CHRM3TRPM8KCNH2HHAT | |
| SCHEMBL22776338 | 0.89 | CHRM3 (0.57) | CHRM3TRPM8KCNH2HHAT | |
| SCHEMBL22776336 | 0.89 | CHRM3 (0.57) | CHRM3TRPM8KCNH2HHAT | |
| SCHEMBL22776994 | 0.88 | TRPM8 (0.50) | CHRM3TRPM8KCNH2 | |
| SCHEMBL22776992 | 0.88 | TRPM8 (0.50) | CHRM3TRPM8KCNH2 | |
| SCHEMBL30965926 | 0.88 | TRPM8 (0.50) | CHRM3TRPM8KCNH2 | |
| SCHEMBL22776993 | 0.88 | TRPM8 (0.50) | CHRM3TRPM8KCNH2 | |
| SCHEMBL22776218 | 0.84 | TRPM8 (0.55) | CHRM3TRPM8KCNH2 | |
| SCHEMBL22784205 | 0.84 | TRPM8 (0.55) | CHRM3TRPM8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113950477-A | Modulators of progranulin and methods of use thereof | 阿库达医疗公司 | 2022-01-18 | — | — | CN | disclosed |