SCHEMBL22787015

SCHEMBL22787015

CCCNC(=O)C(C)(C)CCOC(C)(C)CCC=O

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.39
KDM4C Q9H3R0 1/20 0.31
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23815943 0.79 CNR1 (0.33) CNR1KDM4CDRD2DRD4
SCHEMBL24340799 0.76 CNR1 (0.33) CNR1DRD2DRD4
SCHEMBL27387938 0.76 CNR1 (0.38) CNR1
SCHEMBL24152576 0.75 CNR1 (0.34) CNR1DRD2DRD4
SCHEMBL24340747 0.73 CNR1 (0.33) CNR1DRD2DRD4
SCHEMBL22790789 0.73 CNR1 (0.39) CNR1DRD2DRD4
SCHEMBL19776022 0.72
SCHEMBL19366678 0.72 ACHE (0.40) CNR1
SCHEMBL25446977 0.72 TSHR (0.33)
SCHEMBL25836588 0.72 CNR1 (0.31) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200390894-A1 PROTEOLYSIS-TARGETING CHIMERIC MOLECULES (PROTACS) THAT INDUCE DEGRADATION OF C-MYC PROTEIN NORTHWESTERN UNIVERSITY (US) 2020-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200390894-A1 PROTEOLYSIS-TARGETING CHIMERIC MOLECULES (PROTACS) THAT INDUCE DEGRADATION OF C-MYC PROTEIN MYCBP, MYC, MYCBP2 CNR1 2456/4885KDM4C 734/4885DRD2 3492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.