Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 14/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19366678 | 0.83 | ACHE (0.40) | CNR1ACHEEPHX1 | |
| SCHEMBL22923596 | 0.79 | CASP2 (0.55) | CNR1EPHX1 | |
| SCHEMBL22923591 | 0.76 | CASP2 (0.41) | CNR1EPHX1 | |
| SCHEMBL13543582 | 0.75 | GAA (0.36) | — | |
| SCHEMBL25082958 | 0.75 | EPHX1 (0.43) | CNR1ACHEEPHX1 | |
| SCHEMBL25083035 | 0.75 | EPHX1 (0.43) | CNR1ACHEEPHX1 | |
| SCHEMBL25446977 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL22787015 | 0.73 | CNR1 (0.39) | CNR1DRD2DRD4 | |
| SCHEMBL23815943 | 0.72 | CNR1 (0.33) | CNR1DRD2DRD4 | |
| SCHEMBL24340799 | 0.72 | CNR1 (0.33) | CNR1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252398-A1 | PROTEOLYSIS-TARGETING PROTACS INDUCING DEGRADATION OF C-MIC PROTEIN | NORTHWESTERN UNIVERSITY (US) | 2020-12-17 | — | — | WO | disclosed |