Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22787136 | 0.84 | LMNA (0.36) | GAALMNA | |
| SCHEMBL22787158 | 0.84 | LMNA (0.36) | GAALMNA | |
| SCHEMBL22773520 | 0.81 | LTB4R (0.42) | LTB4RLTB4R2 | |
| SCHEMBL22787133 | 0.71 | LMNA (0.33) | GAALMNA | |
| SCHEMBL22787173 | 0.69 | BRD4 (0.51) | LTB4RGAALTB4R2 | |
| SCHEMBL22787204 | 0.68 | GRK2 (0.33) | GAALMNA | |
| SCHEMBL22787128 | 0.66 | LTB4R (0.38) | LTB4RTSHRFFAR4LTB4R2 | |
| SCHEMBL21098760 | 0.65 | KDM4E (0.41) | FFAR4FFAR1 | |
| SCHEMBL22787205 | 0.64 | — | — | |
| SCHEMBL16829617 | 0.63 | TSHR (0.48) | LTB4RTSHRGAAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020248065-A1 | UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2020-12-17 | — | — | WO | disclosed |