Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.39 |
| ▸ | MAOA | P21397 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14234534 | 0.83 | MAOB (0.43) | MAOBMAOASMN1; SMN2 | |
| SCHEMBL22773712 | 0.80 | MAOA (0.41) | MAOBMAOA | |
| SCHEMBL4761258 | 0.75 | EGFR (0.38) | MAOBMAOA | |
| SCHEMBL2138462 | 0.75 | MAOB (0.41) | MAOBMAOA | |
| SCHEMBL22787134 | 0.73 | HRH3 (0.34) | HRH3 | |
| SCHEMBL22787209 | 0.73 | PPARD (0.32) | — | |
| SCHEMBL14212069 | 0.69 | MAOA (0.39) | MAOBMAOASMN1; SMN2 | |
| SCHEMBL10314897 | 0.69 | HPD (0.53) | MAOBMAOA | |
| SCHEMBL883070 | 0.66 | KMT2A (0.39) | MAOBMAOASMN1; SMN2HRH3 | |
| SCHEMBL10271350 | 0.66 | MAOA (0.49) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020248065-A1 | UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2020-12-17 | — | — | WO | disclosed |