Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952099 | 0.80 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL22772869 | 0.80 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL22772863 | 0.72 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL25098948 | 0.69 | ALDH1A1 (0.39) | GRIN2B | |
| SCHEMBL25154222 | 0.69 | XDH (0.37) | GRIN2B | |
| SCHEMBL29489066 | 0.69 | ALDH1A1 (0.39) | GRIN2B | |
| SCHEMBL30316641 | 0.69 | XDH (0.41) | GRIN2B | |
| SCHEMBL22772886 | 0.67 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL23507946 | 0.67 | XDH (0.36) | GRIN2B | |
| SCHEMBL22772876 | 0.67 | GRIN2B (1.00) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249802-A1 | SUBSTITUTED PYRAZOLO-PYRAZINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |