Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22389454 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL19339517 | 0.77 | ALDH1A1 (0.48) | CYP2A6ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL31171 | 0.76 | CYP2A6 (0.69) | CYP2A6ALDH1A1TYRCYP2A13HSD17B10 | |
| SCHEMBL4956384 | 0.76 | CYP2A6 (0.69) | CYP2A6ALDH1A1TYRCYP2A13HSD17B10 | |
| SCHEMBL21527117 | 0.76 | SMN1; SMN2 (0.67) | CYP2A6ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL26419774 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL862550 | 0.76 | SMN1; SMN2 (0.67) | CYP2A6ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5663817 | 0.74 | KMT2A (0.58) | CYP2A6ALDH1A1TYRHSD17B10ALDH5A1 | |
| SCHEMBL13181220 | 0.74 | APP (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15203333 | 0.74 | GRIN2D (0.48) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392498-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | SOLSTICE BIOLOGICS LTD (IE) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392498-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | HNRNPC, RNASE1, NSUN3 | CYP2A6 4123/4885ALDH1A1 4316/4885TYR 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.